5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine

5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine - Names and Identifiers

Name	5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine
Synonyms	5-[(4-Nitrophenoxy)methyl]-1,3,4-thiadiazol-2-amine 5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine 1,3,4-Thiadiazol-2-aMine, 5-[(4-nitrophenoxy)Methyl]-
CAS	331818-28-1

5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine - Physico-chemical Properties

Molecular Formula	C9H8N4O3S
Molar Mass	252.25
Density	1.536±0.06 g/cm3(Predicted)
Melting Point	198℃ (tetrahydrofuran )
Boling Point	519.6±56.0 °C(Predicted)
pKa	2.60±0.10(Predicted)
Storage Condition	2-8°C

5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine - Introduction

5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine is an organic compound with the chemical formula C9H8N4O4S.

Its nature:
-Appearance: Colorless to light yellow crystalline powder
-Melting point: 191-193 ° C
-Solubility: Almost insoluble in water, can be dissolved under acidic conditions

Its purpose:
-Pesticide: As an insecticide, it can be used to control a variety of insect pests.
-Medicine: In pharmaceutical research, 5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine is used as an intermediate for the synthesis of other compounds.

Its preparation method:
The preparation of 5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine can be carried out by the following steps:
1. First, P-nitrobenzaldehyde is reacted with thiourea to obtain p-nitrophenylthiourea.
2. P-nitrophenylthiourea reacts with methylene chloride to generate 2-chloromethyl -5-(p-nitrophenoxymethylene)-1,3, 4-thiadiazole.
3. Finally, 2-chloromethyl-5-(p-nitrophenoxymethylene)-1,3, 4-thiadiazole was reacted with ammonia to produce 5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine.

Safety Information:
Since 5-[(4-nitrophenoxy)Methyl]-1,3,4-Thiadiazol-2-amine is an organic synthetic compound, it may have certain toxicity. Therefore, the corresponding safety procedures must be observed when using the compound. In addition, it is necessary to properly store and handle the compound to avoid contact with skin, eyes, etc. In case of inadvertent exposure or accidental ingestion, medical help should be sought immediately.

Last Update：2024-04-09 21:04:16